Flosulide NEW
| Price | $1670 | $2180 | $2800 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2025-07-18 |
Product Details
| Product Name: Flosulide | CAS No.: 80937-31-1 |
| Supply Ability: 10g | Release date: 2025/07/18 |
Product Introduction
Bioactivity
| Name | Flosulide |
| Description | Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases. |
| In vitro | Flosulide entirely inhibits the mitotic activity of OSC-2 cells while having no impact on the mitotic activity of OSC-1 cells. Additionally, Flosulide demonstrates a concentration-dependent effect on the OSC-2 cell line by fully suppressing PGE2 production across a range of 1 nM to 100 μM; however, it does not affect prostaglandin (PG) synthesis in OSC-1 cells. |
| In vivo | In normovolemic rats, flosulide enhances renal plasma flow (RPF) and glomerular filtration rate (GFR), while in hypovolemic rats, it reduces these measures at dosages between 5-25 mg/kg. At a dosage of 5 mg/kg, flosulide lowers 6-keto-PGF1alpha, and at 25 mg/kg or following 10 mg/kg of indomethacin, it leads to a decrease in both 6-keto-PGF1alpha and TXB2[1]. Furthermore, flosulide at 0.75 mg/day notably decreases proteinuria compared to aspirin treatment and results in significantly higher plasma protein and albumin levels than those observed in aspirin-treated rats[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | ZK-38997 | ZK38997 | Flosulide | COX-2 | CGP-28238 | CGP28238 |
| Inhibitors Related | Bismuth Subsalicylate | Ibuprofen | Acetaminophen | Salicylamide | Diclofenac sodium | Diclofenac Potassium | trans-Cinnamaldehyde | Paradol | Indomethacin sodium hydrate | Salicylic acid | Glafenine | Revaprazan hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2800.00 |
VIP3Y
|
TargetMol Chemicals Inc.
|
2026-04-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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