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Postion:Product Catalog >API>Nervous system drugs>Antidepressants, Antimanics drugs>Fluvoxamine
Fluvoxamine
  • Fluvoxamine

Fluvoxamine NEW

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Package 1removed
Supply Ability: 10g
Update Time: 2026-07-17

Product Details

Product Name: Fluvoxamine CAS No.: 54739-18-3
Purity: 99.91% Supply Ability: 10g
Release date: 2026/07/17

Product Introduction

Bioactivity

NameFluvoxamine
DescriptionFluvoxamine (DU-23000) is a selective, orally available 5-HT and serotonin reuptake inhibitor (SSRI) exhibiting antidepressant effects.
In vivoFluvoxamine effectively inhibits the uptake of serotonin (5-HT) by platelets and brain synaptosomes [1]. The antagonistic effect of fluvoxamine on reserpine-induced lowering of pentylenetetrazol (PTZ) seizure threshold can be attributed to its influence on 5-HT uptake [1]. In contrast to desipramine and imipramine, fluvoxamine did not elicit stimulant effects in rats after administration of a rapidly acting reserpine-like compound [1]. Fluvoxamine improves combat-related PTSD symptoms but is ineffective for depressive symptoms [2]. Due to high dropout rates and the lack of a placebo control group, the reliability of current findings is limited, and future controlled studies on fluvoxamine for PTSD treatment are needed [2]. When ethanol is available with food, fluvoxamine is less effective in reducing ethanol self-administration than when ethanol is available alone [ED₅₀ values were 4.0 (2.7–5.9) and 5.1 (4.3–6.0), respectively] [3]. Under each condition where food was available, fluvoxamine had no significant effect on food intake [3]. These results indicate that the efficacy of fluvoxamine in suppressing ethanol-maintained behavior is influenced by whether ethanol is concurrently available with food reinforcement [3].
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 250 mg/mL (785.35 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (10.37 mM), Sonication is recommended.
10% DMSO+90% Saline : 10 mg/mL (31.41 mM), Suspension.
KeywordsFluvoxamine
Inhibitors RelatedAlverine citrate | Sevoflurane | Dapoxetine hydrochloride | Cefaclor monohydrate | Clozapine N-Oxide | 1,8-Cineole | Dopamine hydrochloride | Cloperastine hydrochloride | Mianserin hydrochloride | Trazodone hydrochloride | Cinchonidine | Doxepin hydrochloride
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Neuronal Signaling Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Fluorochemical Library | GPCR Compound Library | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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