Folic acid NEW
| Price | $45 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Folic acid | CAS No.: 59-30-3 |
| Purity: 99.27% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Folic acid |
| Description | Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production and maintenance of new cells. Folic acid deficiency can lead to anemia, neural tube closure defects, tumors, aging, and other diseases. |
| Cell Research | To determine the effect of FA supplementation on BRCA1 and BRCA2 mRNA expression, all cell lines were treated with 0, 25, 50, 75, or 100 nmol/L FA for 72 hours before harvesting in TRI Reagent according to the manufacturer’s instructions. (Only for Reference) |
| In vitro | METHODS: HUVEC cells were treated with Folic acid (2.5-100 µM) for 48 h. Cell proliferation was detected using xCELLigence RTCA real-time cell analyzer. RESULTS: Folic acid increased cell proliferation in the HUVEC cell line using a cytometric index to determine the EC50 dose of 50 µL.[1] METHODS: Neural tube explants were treated with Folic acid (90 µM) for 3 h and morphology was observed using microscopy. RESULTS: In the presence of Folic acid, cell migration from the neural tube explants was detected in 80% of the cultures within 2-3 h. The first cell to leave the initial explant was the first cell to leave the neural tube explant. The first cells leaving the initial explants were tightly organized neuroepithelial cells and the explants were firmly attached to the fibronectin layer. [2] |
| In vivo | METHODS: To investigate the role of Folic acid (1-100 mg/kg) in a behavioral model of depression, Swiss mice were administered Folic acid (1-100 mg/kg) in a single gavage dose and subjected to the forced swimming test (FST) and tail suspension test (TST). RESULTS: Oral administration of Folic acid reduced immobilization time in the FST (50-100 mg/kg) and TST (10-50 mg/kg). Folic acid produces antidepressant-like effects in the FST and TST. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2.5 mg/mL (5.66 mM), suspension.In vivo: Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. DMSO : 25 mg/mL (56.63 mM), Sonication is recommended. |
| Keywords | Vitamin B-9 | Vitamin B 9 | VB9 | RNASynthesis | RNA Synthesis | nutrient | ntidepressant-like | neural tube defects | Inhibitor | inhibit | folic deficiency | Folic acid | EndogenousMetabolite | Endogenous Metabolite | DNASynthesis | DNA/RNA Synthesis | DNA Synthesis |
| Inhibitors Related | Sucrose | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Drug Repurposing Compound Library | Natural Product Library | Microbial Natural Product Library | Tobacco Monomer Library | Natural Product Library for HTS | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Gut Microbial Metabolite Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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