FTY720 (S)-Phosphate NEW
| Price | $1460 | $2230 |
| Package | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: FTY720 (S)-Phosphate | CAS No.: 402616-26-6 |
| Supply Ability: 10g | Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | FTY720 (S)-Phosphate |
| Description | FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in research on acute inflammatory diseases, including acute lung injury. |
| In vitro | FTY720 (S)-Phosphate (0.01-50 μM) also reduces β-arrestin recruitment to S1PR1. FTY720 (S)-Phosphate (Tys, 1 μM) maintains S1PR1 protein expression, enhances the human pulmonary artery endothelial cells barrier via S1PR1. But it shows no effect on inducing ubiquitination of S1PR1 [1]. |
| In vivo | FTY720 (S)-Phosphate, administered intraperitoneally at a dose of 0.5 mg/kg, maintains S1PR1 expression in mouse lungs and offers protection against acute lung injury (ALI) induced by bleomycin. Additionally, it reduces leukocyte infiltration in the lung tissues of mice injured with bleomycin [1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | S1PR1 | FTY720P | FTY-720 Phosphate | FTY720 Phosphate | FTY-720 (S)-Phosphate | FTY720 (S)Phosphate | FTY720 (S) Phosphate | FTY 720 Phosphate |
| Inhibitors Related | Fingolimod hydrochloride | SLP9101555 | BMS-960 | LX-2931 | Sphingosine-1-phosphate | CYM50374 | K145 hydrochloride | ASP-4058 | Siponimod | MP-A08 | Ozanimod | W140 HBr |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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