Product Details
| Product Name:
GNE-490 |
CAS No.:
1033739-92-2 |
| Purity:
99.77% |
Supply Ability:
10g |
| Release date:
2025/10/26 |
Product Introduction
Bioactivity
| Name | GNE-490 |
| Description | GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50 = 750 nM). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (129.38 mM), Sonication is recommended.
|
| Keywords | PI3Kδ | PI3Kγ | PI3Kβ | PI3Kα | PI3K | Phosphoinositide 3-kinase | mTOR | MCF7.1 | Mammalian target of Rapamycin | Inhibitor | inhibit | GNE-490 | GNE490 | GNE 490 | breast cancer |
| Inhibitors Related | Musk ketone | Myricetin | Erucic acid | 4-Methylbenzylidene camphor | (±)-α-Bisabolol | Berberine hydrogen sulphate | Isoprenaline hydrochloride | Thymoquinone | Quercetin | Dihydromyricetin | Berberine sulfate | Apilimod |
| Related Compound Libraries | Reprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Antioxidant Compound Library | Inhibitor Library | Metabolism Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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