HDAC1/MAO-B-IN-1 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: HDAC1/MAO-B-IN-1 | CAS No.: 2759855-37-1 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | HDAC1/MAO-B-IN-1 |
| Description | HDAC1/MAO-B-IN-1 has the potential to be used in the Alzheimer's disease research. HDAC1/MAO-B-IN-1 is a potent and selective inhibitor of HDAC1/MAO-B that can cross the blood-brain barrier. The IC50 values of HDAC1/MAO-B-IN-1 for HDAC1 and MAO-B are 21.4 nM and 99.0 nM, respectively [1]. |
| In vitro | HDAC1/MAO-B-IN-1 (compound 1f) inhibits hMAO-B, hMAO-A, and hHDAC1 with IC50 values of 99.0 nM, 9923.0 nM, and 21.4 nM, respectively [1]. At 50 μM over 24 hours, it shows neuroprotective effects and reduces reactive oxygen species (ROS) production in PC12 cells, as confirmed by a Cell Viability Assay [1]. |
| In vivo | Administered intragastrically (i.g.) at 20 mg/kg, HDAC1/MAO-B-IN-1 demonstrates favorable permeability across the blood-brain barrier (BBB) [1]. When administered intraperitoneally (i.p.) at 15 mg/kg for 15 consecutive days, it enhances the learning and memory functionalities in ICR mice, both male (6-8 weeks old) and female (20-25 g) models [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Panobinostat | Theophylline monohydrate | Methoxyacetic acid | Sodium 4-phenylbutyrate | 1,4-Naphthoquinone | Curcumin | Valproic Acid | Paeonol | Hydroxylamine hydrochloride | Sodium butanoate | β-Aminopropionitrile | 4-Phenylbutyric acid |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1520.00/25mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-07-20 | |
| $155.00/1mg |
VIP6Y
|
TargetMol Chemicals Inc.
|
2025-09-11 | |
| $0.00/10mg |
VIP8Y
|
Guangzhou PI PI BIOTECH INC
|
2022-01-12 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY