Product Details
| Product Name:
Hernandezine |
CAS No.:
6681-13-6 |
| Purity:
99.53% |
Supply Ability:
10g |
| Release date:
2026/07/27 |
Product Introduction
Bioactivity
| Name | Hernandezine |
| Description | Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells. |
| In vitro | Hernandezine inhibits LPS-induced TNF-α expression/production in human macrophage cell lines (THP-1 and U93). Hernandezine inhibits the transport function of ABCB1, and enhances drug-induced apoptosis in cancer cells. Hernandezine significantly resensitizes ABCB1-overexpressing cancer cells to multiple chemotherapeutic drugs at nontoxic, nanomolar concentrations[1]. |
| Storage | Keep away from direct sunlight,Store at low temperature,
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | TNF-α | ROS | Pgp | Hernandezine | AMPK | ABCB1 |
| Inhibitors Related | Ethoxyquin | Kaolin | Allopurinol | Imeglimin hydrochloride | Triphenyl phosphate | 1,8-Cineole | Ethyl linoleate | Magnesium acetate tetrahydrate | L-Cystine | Dimethyl phthalate | 6-PPD | Chitosan oligosaccharide |
| Related Compound Libraries | Rare Natural Product Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1.00
|
VIP7Y
|
Career Henan Chemical Co
|
2020-01-13 |
United States