Hydroxy Itraconazole NEW
| Price | $278 | $619 | $993 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-09 |
Product Details
| Product Name: Hydroxy Itraconazole | CAS No.: 112559-91-8 |
| Purity: 99.59% | Supply Ability: 10g |
| Release date: 2025/11/09 |
Product Introduction
Bioactivity
| Name | Hydroxy Itraconazole |
| Description | Hydroxy Itraconazole (R63373) is a triazole compound with antifungal activity for the study of malignant tumors. |
| In vitro | Hydroxy Itraconazole is considered to have antifungal effects in vitro. It contains a triazole ring in its structure and is capable of inhibiting the CYP3A enzyme. [1] |
| In vivo | Plasma concentrations of Hydroxy Itraconazole do not correlate well with ITZ doses, probably because the process of forming Hydroxy Itraconazole is saturated. Factors such as serum albumin and GFR affect the pharmacokinetics of ITZ and Hydroxy Itraconazole. When considering antifungal activity, it is important to look not only at plasma concentrations of ITZ, but also at plasma concentrations of Hydroxy Itraconazole. However, the pharmacokinetics of Hydroxy Itraconazole in immunocompromised patients receiving oral ITZ solutions are similar to those of ITZ. Therefore, since plasma concentrations of ITZ and Hydroxy Itraconazole are highly correlated, determining plasma concentrations of both should be sufficient from a clinical standpoint. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80.00 mg/mL (110.86 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (4.57 mM), Sonication is recommended. |
| Keywords | R63373 | R 63373 | Hydroxyitraconazole | Hydroxy Itraconazole | Antifungal |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Adipic dihydrazide | Ampicillin sodium | Acetic Acid | Doxycycline (hyclate) | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Copper(Ⅱ) Sulfate | Doxycycline | BES |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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