Ipragliflozin (L-Proline) NEW
| Price | $30 |
| Package | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Ipragliflozin (L-Proline) | CAS No.: 951382-34-6 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Ipragliflozin (L-Proline) |
| Description | Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6. |
| In vitro | Ipragliflozin selectively and potently inhibits human, rat, and mouse SGLT2 at nanomolar ranges and exhibits stability against intestinal glucosidases. |
| In vivo | Following oral administration, ipragliflozin demonstrates favorable pharmacokinetic properties and dose-dependently enhances urinary glucose excretion, with effects lasting over 12 hours in normal mice. This increase in urinary glucose excretion is significant at doses of 0.3 mg/kg or higher. Additionally, a single dose of ipragliflozin effectively increases urinary glucose excretion, lowers blood glucose and plasma insulin levels, and ameliorates glucose intolerance. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | SGLT2 | L-Proline | Ipragliflozin (LProline) | Ipragliflozin (L Proline) | Ipragliflozin |
| Inhibitors Related | Dapagliflozin ((2S)-1,2-propanediol, hydrate) | Ertugliflozin L-pyroglutamic acid | Dapagliflozin | Sotagliflozin | Ipragliflozin | Canagliflozin hemihydrate | Phlorizin | Phloretin | Sergliflozin A | Canagliflozin | Empagliflozin | Ertugliflozin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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