Itaconate-alkyne NEW
| Price | $67 | $163 | $263 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-23 |
Product Details
| Product Name: Itaconate-alkyne | CAS No.: 2454181-83-8 |
| Purity: 99.78% | Supply Ability: 10g |
| Release date: 2025/10/23 |
Product Introduction
Bioactivity
| Name | Itaconate-alkyne |
| Description | Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative, site-specific chemoproteomic profiling of itaconate in inflammatory macrophages, facilitating biochemical evaluation and proteomic analysis of its direct targets. |
| In vitro | Itaconate-alkyne can capture itaconate targets including DNA damage-binding protein 1 (DDB1), Gelsolin (GSN), ATP-citrate synthase (ACLY) and Adenylate kinase 2 (AK2) in inflammatory macrophages[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 245 mg/mL (1028.20 mM), Sonication is recommended. |
| Keywords | site-specific | Raw264.7 | quantitative | probe | NRF-2 | LPS | labeling | Itaconation | Itaconate-alkyne | Itaconatealkyne | Itaconate alkyne | Itaconate | Inhibitor | inhibit | IL-1β | GSN | DDB1 | chemoproteomic | bioorthogonal | antiinflammatory | AK2 | ACLY |
| Related Compound Libraries | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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