Product Details
| Product Name:
K00135 |
CAS No.:
869650-21-5 |
| Purity:
98.16% |
Supply Ability:
10g |
| Release date:
2025/09/28 |
Product Introduction
Bioactivity
| Name | K00135 |
| Description | K00135 (IMIDAZOPYRIDAZIN 1) is a selective inhibitor of Pim kinases and can be used in studies about gastric cancer and antileukemic therapeutics. |
| In vitro | K00135 dose-dependently impairs the survival of murine Ba/F3 cells that have been rendered cytokine independent by overexpression of human PIMs. K00135 impairs survival and clonogenic growth of a panel of human acute leukemia cells. Exposure of K00135 significantly suppresses in vitro growth of leukemic blasts from five acute myelogenous leukemia patients but not of normal umbilical cord blood mononuclear cells[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 4.4 mg/mL (14.36 mM), Sonication is recommended.
|
| Keywords | Pim | K00135 |
| Inhibitors Related | XL413 hydrochloride | HJ-PI01 | SGI-1776 | CK2/ERK8-IN-1 | M-110 | (Z)-SMI-4a | CX-6258 hydrochloride | Pim-1 kinase inhibitor 4 | Pim-1/2 kinase inhibitor 1 | Pim-1 kinase inhibitor 8 | XL413 xHCl | TP-3654 |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Kinase Inhibitor Library | JAK-STAT Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States