Product Details
| Product Name:
KLH45 |
CAS No.:
1632236-44-2 |
| Purity:
99.71% |
Supply Ability:
10g |
| Release date:
2025/10/20 |
Product Introduction
Bioactivity
| Name | KLH45 |
| Description | KLH45 is an effective and selective inhibitor of Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2(IC50 = 1.3 nM). |
| In vitro | In Neuro2A cells, KLH45 (25 nM) completely inhibits DDHD2 (>95%)[1]. In fatty acid-supplemented DDHD2-expressing cells, KLH45 (2 μM) increases LD formation and selectively blocks DDHD2 activity[2]. |
| In vivo | KLH45 (20 mg/kg) significantly elevates brain triglycerides in DDHD2−/− mice[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 162.0 mg/mL (353.3 mM), Sonication is recommended.
|
| Keywords | KLH45 | DDHD2 |
| Inhibitors Related | PTP1B-IN-22 | Disodium monofluorophosphate | β-Glycerophosphate disodium salt pentahydrate | Idoxuridine | Tartaric acid disodium dihydrate | Cyclosporine | Stearic acid | Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride | CaMKP Inhibitor | L-Ascorbic acid 2-phosphate magnesium | Cyclosporin A | Trimyristin |
| Related Compound Libraries | Glycometabolism Compound Library | Bioactive Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Phosphatase Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:841301-32-4
$32.00 / 1mg
-
CAS:146426-40-6
$34.00 / 2mg
-
CAS:910487-58-0
$37.00 / 1mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States