Kuwanon H NEW
| Price | $56 | $147 | $228 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-24 |
Product Details
| Product Name: Kuwanon H | CAS No.: 76472-87-2 |
| Purity: 97.09% | Supply Ability: 10g |
| Release date: 2025/10/24 |
Product Introduction
Bioactivity
| Name | Kuwanon H |
| Description | Kuwanon H is a specific antagonist for the gastrin-releasing peptide (GRP) -preferring receptor with Ki values of 290 nM and can be useful for studying the physiological and pathological role of GRP. Kuwanon H is a potent non-peptide bombesin receptor antagonist. |
| In vitro | Kuwanon G and H, isolated from the methanol extract of Morus bombycis, inhibited specific binding of [125I]gastrin-releasing peptide (GRP) to GRP-preferring receptors in murine Swiss 3T3 fibroblasts with Ki values of 470 and 290 nM, respectively. Kuwanon H was one order of magnitude less potent for inhibiting [125I]bombesin binding to neuromedin B (NMB)-preferring receptors in rat esophagus membranes. This compound antagonized bombesin-induced increases in the cytosolic free calcium concentration and GRP-induced DNA synthesis in Swiss 3T3 cells. |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (65.72 mM), Sonication is recommended. |
| Keywords | Kuwanon H | Inhibitor | inhibit | GPR | BombesinReceptor | Bombesin Receptor |
| Inhibitors Related | Vincamine | Monomethyl fumarate | Questiomycin A | 3-Hydroxyoctanoic Acid | Azathioprine | CRTh2 antagonist 2 | Fezagepras sodium | Benzyl nicotinate | TUG-1375 | CAY10595 | Timapiprant | NF-56-EJ40 |
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Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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