L 012 sodium salt NEW

Product Introduction: L 012 Sodium Salt (CAS: 143556-24-5)

Chemical Name:
Sodium 8-amino-5-chloro-1-oxo-7-phenyl-2H-pyrido[3,4-d]pyridazin-4-olate

Molecular Formula:
C₁₃H₈ClN₄NaO₂

Molecular Weight:
310.67 g/mol

IUPAC Name:
Sodium 8-amino-5-chloro-1-oxo-7-phenyl-2H-pyrido[3,4-d]pyridazin-4-olate

Chemical Structure:
A luminol analogue featuring a pyrido[3,4-d]pyridazine core substituted with an amino group, chlorine atom, phenyl ring, and sodium carboxylate group.

Chemical Properties

1. Appearance:

• White to yellow solid.

2. Solubility:

• Soluble in water (up to 3.0 mg/mL at 9.6 mM with sonication and heating to 60°C).

• Highly soluble in DMSO (up to 45.0 mg/mL at 144.8 mM with sonication).

3. Stability:

• Store at -20°C for long-term stability.

• Avoid exposure to light and moisture.

4. Chemical Reactivity:

• Acts as a chemiluminescent probe, reacting with reactive oxygen species (ROS) and reactive nitrogen species (RNS) to produce light.

Applications & Uses

1. Chemiluminescent Probe:

• Widely used for detecting superoxides (O₂•⁻) derived from NADPH oxidase (Nox) in vitro and in vivo.

• Enables the identification and screening of Nox inhibitors.

2. Biological Research:

• Utilized in monitoring ROS/RNS levels in cellular and animal models, including inflammation studies.

• Demonstrates strong chemiluminescent signals in response to ROS generated by activated neutrophils, macrophages, and endothelial cells.

3. Pharmaceutical Development:

• Serves as a tool for drug discovery, particularly in evaluating antioxidants and anti-inflammatory agents.

4. Environmental & Industrial Applications:

• Potential use in detecting ROS/RNS in environmental samples or industrial processes.

Key Advantages

1. High Sensitivity:

• Offers superior chemiluminescent intensity compared to traditional probes like MCLA, making it ideal for low-level ROS detection.

2. Versatility:

• Suitable for both in vitro (e.g., cell cultures) and in vivo (e.g., animal models) experiments.

3. Ease of Use:

• Simple protocol for solution preparation and detection, with compatibility with standard luminometers.

4. Reliable Performance:

• Consistent results across various biological systems, ensuring reproducibility in research.

Quality & Compliance

• Purity: Available in high-purity grades (≥95% HPLC), ensuring accurate and reliable experimental outcomes.

• Regulatory Compliance: Manufactured under strict quality control standards, suitable for academic and industrial research.

Packaging & Storage

• Packaging:

• Available in 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg, 1 g, and larger quantities upon request.

• Storage:

• Store at -20°C in a desiccated environment. Protect from light and moisture.

• Shelf life: 2 years when stored properly.

Why Choose L 012 Sodium Salt?

• Leading Supplier:

• Partner with a trusted provider offering competitive pricing, fast delivery, and exceptional customer support.

• Technical Expertise:

• Access to expert guidance for protocol optimization and troubleshooting.

• Custom Solutions:

• Tailored packaging and bulk orders to meet your specific research needs.

For inquiries or to place an order, contact us today!

 Company Profile

     Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. 

     We are committed to providing high-quality chemical products and comprehensive solutions to meet the diverse needs of the global market.

     Our research and development team possesses profound professional knowledge and extensive industry experience, dedicated to developing cutting-edge chemical materials to drive technological progress and industrial development. Our production facilities are equipped with state-of-the-art technology and a stringent quality control system to ensure product consistency and reliability.

     As a pioneer in the industry, we not only offer standardized products but also customize chemicals and services according to the specific needs of our customers. Our goal is to become a trusted partner for global customers through continuous technological innovation and superior customer service.

Our Advantage

Quality control

Based on industry norms, customer requirements, and internal quality objectives, we establish clear quality standards. By monitoring the production process in real-time, we ensure that every step conforms to the predetermined quality standards.

Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.

Technological innovation

Our technological innovation is reflected in the development of new materials that are at the leading edge of the industry. These materials not only possess higher performance and lower costs but also enable sustainable use within an environmentally friendly production process.

Competitiveness

Based on rich experience in material development and production, we have established a more scientific cost control system. By ensuring product quality, and through refined management and continuous process optimization, we offer more competitive prices.

Word of mouth

Adhering to the principle of customer first, customer first, and honest service, we have established long-term business relationships with customers and are deeply welcomed and trusted by them.

Rich experience

Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.

Safe and fast delivery

We will arrange shipment of spot products as soon as we receive payment.

Customized products are determined based on the synthesis time of different products.

Excellent pre-sales and after-sales service

Pre sales:

We are committed to providing the most favorable quotes and detailed information about our products and company.

After-sale service:

We assist buyers in customs clearance by providing necessary documents and information.

If there is any dispute over product quality, we are committed to providing the best solution.

Our packaging and shipping

• Packaging: 

1kg/bag or bottle, 25kg/drum, 50kg/drum, 200L/drum, 1T/bag or IBC drum, standard export packaging or packaging required by customers.

• Shipping

• Delivery:

Within 7 days after receiving your payment

Contact information

For more details, pls contact us freely.

Email: jiuyitime@fdachem.com

 Sincerely hope to establish friendly business relationships with new and old customers, and jointly create a beautiful future for the fine chemical industry!