LCB-2853 NEW
| Price | $700 | $1800 |
| Package | 1mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: LCB-2853 | CAS No.: 141335-10-6 |
| Purity: 97.15% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | LCB-2853 |
| Description | LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects. |
| In vivo | In dog coronary stenosis, LCB 2853 demonstrates high efficacy with an ED50 of 7.2 μg/kg. In rat venous thrombosis induced by venous injury and blood stasis, perfused LCB 2853 reduces thrombus weight in a dose-dependent manner with an ED50 of 220 μg/kg/min[1]. In vivo, LCB 2853 shows an ED50 below 1 mg/kg i.v. against platelet aggregation and vasoconstriction, observed in rat arachidonic acid (AA)-induced thrombocytopenia or U 46619-induced hypertension (ED50 = 0.25 and 0.16 mg/kg) and in AA-induced sudden death in mice (ED50 = 0.44 mg/kg). Additionally, LCB 2853 effectively blocks U 46619-induced bronchoconstriction after i.v. administration (ED50 = 18.4 μg/kg)[2]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | TXA2R | TXA2 Receptor | LCB-2853 | LCB2853 | LCB 2853 |
| Inhibitors Related | PHYTOL | Rosiglitazone | Daidzein | Magnesium acetate tetrahydrate | Maltitol | 5-Aminosalicylic Acid | 2,3-Butanediol | Rebamipide | NPC 15199 | Cloxiquine | D-Arabinose | p-Hydroxycinnamic acid |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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| $71.00 |
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TargetMol Chemicals Inc.
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2026-07-27 | |
| $700.00 |
VIP5Y
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TargetMol Chemicals Inc.
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2026-09-10 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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