LCL521 dihydrochloride NEW
| Price | $987 | $1360 | $2190 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-23 |
Product Details
| Product Name: LCL521 dihydrochloride | CAS No.: 1226759-47-2 |
| Supply Ability: 10g | Release date: 2025/10/23 |
Product Introduction
Bioactivity
| Name | LCL521 dihydrochloride |
| Description | LCL521 dihydrochloride is a dual inhibitor of acid ceramidase (ACDase) and lysosomal acid sphingomyelinase (ASMase). By targeting these lysosomal enzymes, LCL521 dihydrochloride modulates sphingolipid metabolism, with potential applications in cancer and metabolic disorder research. |
| In vitro | LCL521 dihydrochloride is a potent cellular ACDase inhibitor at a concentration of 1 µM. At a higher concentration (10 µM), LCL521 dihydrochloride additionally exerts a reducing effect on the α-form of ACDase. Specifically, in MCF7 cells, LCL521 dihydrochloride (10 µM) induces a time-dependent decrease in the α-ACDase form, which is observable within 1 to 5 hours.[1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 20 mg/mL (30.04 mM), Sonication is recommended. DMSO : 80 mg/mL (120.18 mM), Sonication is recommended. |
| Keywords | LCL-521 Dihydrochloride | LCL521 dihydrochloride | LCL-521 | LCL521 | LCL 521 Dihydrochloride | LCL 521 | ACDase, ASMase | 1,3DMG-B13 Dihydrochloride | 1,3DMG-B13 |
| Inhibitors Related | Neomycin sulfate | 1-Naphthaleneacetic acid potassium salt | Difluprednate | trans-Benzylideneacetone | Benzylideneacetone | Omeprazole | (E/Z)-Polydatin | Indomethacin | Fluticasone (propionate) | 1-Naphthaleneacetic acid | Darapladib | Lansoprazole |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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