LMD-009 NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: LMD-009 | CAS No.: 950195-51-4 |
| Supply Ability: 10g | Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | LMD-009 |
| Description | LMD-009 is a non-peptide, selective CCR8 agonist that mediates chemotaxis, inositol phosphate accumulation, and calcium release, with an EC50 of 11–87 nM. |
| In vitro | Methods: COS-7 cells were treated with LMD-009 (0-20 nM, 90 minutes) and cell viability was measured. Results: LMD-009 stimulated inositol phosphate accumulation in COS-7 cells expressing the human CCR8 receptor with an EC50 value of 11 nM. It did not inhibit any other human chemokine receptors. Methods: Chinese hamster ovary cells were treated with LMD-009 (0-100 nM, 1 hour) and cell viability was measured. Results: The EC50 value of LMD-009 for regulating calcium release in Chinese hamster ovary cells was 87 nM. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (10.6 mM), Sonication is recommended. DMSO : 200 mg/mL (424.1 mM), Sonication is recommended. |
| Keywords | LMD-009 | LMD 009 | CCR8 |
| Inhibitors Related | AZD2098 | MLN-3897 TFA | Artemotil | CCR2 antagonist 5 | INCB-9471 | CCR3 antagonist 1 | Maraviroc | BMS-817399 | PF-4136309 | Pirfenidone | Vercirnon | CCR6 antagonist 1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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