ML-792 NEW
| Price | $84 | $122 | $197 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-11 |
Product Details
| Product Name: ML-792 | CAS No.: 1644342-14-2 |
| Purity: 99.82% | Supply Ability: 10g |
| Release date: 2025/11/11 |
Product Introduction
Bioactivity
| Name | ML-792 |
| Description | ML-792 is a specific small ubiquitin-like modifier activating enzyme (SUMO) inhibitor. ML-792 selectively inhibits SAE/SUMO1 and SAE/SUMO2 with IC50 of 3 and 11 nM. |
| In vitro | METHODS: Cell lines (MDA-MB-468, HCT116,Colo-205, MDA-MB-231, A375) were treated with ML-792 (1 nM -10 μM) for 72 hours. Cell viability was determined using the CellTiter-Glo viability assay. RESULTS ML-792 showed a dose-dependent viability effect in all cell lines tested, with an EC50 value of 0.06 μM in MDA-MB-468 cells and 0.45 μM in A375 cells. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 255 mg/mL (462.45 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (9.07 mM), Sonication is recommended. |
| Keywords | Ubiquitin ligase | Ubiquitin conjugating enzyme | Ubiquitin activating enzyme | SAE/SUMO2 | SAE/SUMO1 | ML-792 | ML792 | ML 792 | Inhibitor | inhibit | E3Enzyme | E3 ligating enzyme | E3 Enzyme | E2Enzyme | E2 Enzyme | E2 conjugating enzyme | E1Enzyme | E1/E2/E3 Enzyme | E1 Enzyme | E1 activating enzyme |
| Inhibitors Related | NSC697923 | PYZD-4409 | NAcM-OPT | Nutlin-3 | RG7112 | Pevonedistat | PYR-41 | NSC232003 | NAE-IN-M22 | Indole-3-carbinol | Idasanutlin | Navtemadlin |
| Related Compound Libraries | Bioactive Compound Library | Ubiquitination Compound Library | HIF-1 Signaling Pathway Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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