ML334 NEW
| Price | $49 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-27 |
Product Details
| Product Name: ML334 | CAS No.: 1432500-66-7 |
| Purity: 98.06% | Supply Ability: 10g |
| Release date: 2026/07/27 |
Product Introduction
Bioactivity
| Name | ML334 |
| Description | ML334 (LH601A) is a transmembrane and potent NRF2 activator that inhibits Keap1-NRF2 protein interactions to ameliorate myocardial infarction-induced cardiac fibrosis by inhibiting cardiac fibroblast activation and proliferation. |
| In vitro | Treatment of HEK293 cells with ML334 (LH601A; 50-100 μM; 6-16 hours) increases NQO1 and TRX1 mRNA levels by 2 to 3 times at both 6 and 16 hours. Additionally, at 6 hours, ML334 enhances HO-1 mRNA expression by 4 to 7 times, with a relatively smaller change in fold increase observed at 16 hours [2]. ML334 (LH601A; 50-100 μM; 16 hours; HEK293 cells) induces the expression of HO-1 and TRX1 proteins in HEK293 cells [2]. Furthermore, ML334 (LH601A) stimulates the expression and nuclear translocation of NRF2 in HEK293 cells [2]. |
| Storage | Store at low temperature,Store under nitrogen, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (11.2 mM), Sonication is recommended. DMSO : 30 mg/mL (67.19 mM), Sonication is recommended. Ethanol : 30 mg/mL (67.19 mM), Sonication is recommended. |
| Keywords | ML-334 | ML334 | ML 334 | KEAP1-Nrf2 |
| Inhibitors Related | PHYTOL | TBHQ | Aceglutamide | Dimethyl fumarate | Pyridoxine | Curcumin | L-Methionine | L-Cystine | Thiamine hydrochloride | 4-hydroxyphenylacetic acid | Finasteride | Kopexil |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $49.00 |
VIP5Y
|
TargetMol Chemicals Inc.
|
2026-07-27 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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