Product Details
| Product Name:
MOTS-c(Human) Acetate（1627580-64-6 free） |
Purity:
100.00% |
| Supply Ability:
10g |
Release date:
2025/10/10 |
Product Introduction
Bioactivity
| Name | MOTS-c(Human) Acetate（1627580-64-6 free） |
| Description | MOTS-c(Human) Acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity. |
| In vitro | MOTS-c inhibits the folate cycle at the level of 5Me-THF, resulting in an accumulation of AICAR [5-aminoimidazole-4-carboxamide ribonucleotide). MOTS-c also increases cellular NAD+ levels, which are also nucleotide precursors[1]. |
| In vivo | MOTS-c injections in mice show activation of skeletal muscle AMPK and increased the level of its downstream glucose transporter GLUT4. MOTS-c may also act as a potential mitochondrial signal that mediates an exercise-induced mitohormesis response, thereby stimulating physiological adaptation and increased tolerance to exercise[1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 10 mM, Sonication is recommended.
|
| Keywords | MOTSc(Human) Acetate（1627580646 free） | MOTS-c(Human) Acetate | MOTS c(Human) Acetate（1627580 64 6 free） | AMPK | 1627580-64-6 free |
| Inhibitors Related | AMPK activator 12 | AICAR | RGX-202 | Adenosine monophosphate | Adenosine 5'-monophosphate monohydrate | Metformin | Methyl cinnamate | Metformin hydrochloride | Chitosan oligosaccharide | Buformin hydrochloride | HTH-01-015 | AMPK activator 4 |
| Related Compound Libraries | Anti-Diabetic Compound Library | Peptide Compound Library | NO PAINS Compound Library | Neuronal Differentiation Compound Library | AMPK-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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