Product Details
| Product Name: Nintedanib (BIBF 1120) | CAS No.: 656247-17-5 |
| Min. Order: 1g | Purity: 98% HPLC |
| Supply Ability: 100kg | Release date: 2024/11/19 |
BIBF 1120 is a potent triple angiokinase inhibitor with IC50 values of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β, respectively nM and 59 nM/65 nM. It can simultaneously block the signal transduction pathways of vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR). Nintedanib benefited the vast majority of the IPF patient population from slowing disease progression, as demonstrated by a 50% reduction in lung function decline in patients, including patients with early-stage disease (forced vital capacity [FVC] as a percentage of predicted >90%), high-resolution computed tomography (HRCT) did not detect honeycombing lung lesions and/or patients with emphysema.
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- Since: 2014-09-09
- Address: No.28 Hua Long Road,Ji Nan City,China
+86-13153181156
sales@sdperfect.com

China