NOTA NEW
| Price | $36 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-03-13 |
Product Details
| Product Name: NOTA | CAS No.: 56491-86-2 |
| Purity: 98.04% | Supply Ability: 10g |
| Release date: 2026/03/13 |
Product Introduction
Bioactivity
| Name | NOTA |
| Description | NOTA is a multifunctional chelator capable of forming stable complexes with metal ions and is commonly used in radiopharmaceuticals, molecular imaging and targeted nuclear therapy. |
| In vitro | [⁶⁴Cu]NOTA-pentixather showed high affinity for CXCR4 in Jurkat T cells (IC₅₀ = 14.9 ± 2.1 nM) and was efficiently internalized in Chem-1 cells stably expressing human CXCR4[1].[⁶⁸Ga]NOTA-RGD showed a high binding affinity for the αvβ₃ integrin (IC₅₀ = 27.9 ± 6.8 nM) in receptor binding assays, indicating effective targeting of integrin expression associated with angiogenesis[2]. |
| In vivo | In SCID mice bearing Daudi lymphoma, intravenous injection of [⁶⁴Cu]NOTA-pentixather resulted in high tumor uptake (13.1 ± 1.5% ID/g at 1.5 h post-injection), exceeding uptake in all other organs[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 110 mg/mL (362.67 mM), Sonication is recommended. |
| Keywords | NOTA |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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