Product Details
| Product Name:
NRA-0160 |
CAS No.:
204718-47-8 |
| Supply Ability:
10g |
Release date:
2025/07/21 |
Product Introduction
Bioactivity
| Name | NRA-0160 |
| Description | NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM) |
| In vivo | NRA0160 dose-dependently and significantly reverses the effects of MAP on both A9 and Al0 dopamine neurons.?NRA0160 is slightly more potent in reversiig the effects of MAP on A10 (ED50 = 1.0 mg/kg) than on A9 dopamine neurons (ED50 = 1.3 mg/kg).?NRA0160 reverses the effect of AP0 on both A9 and A10 dopamine neurons.?ED50 values for the effects of NRA0160 on APO-induced inhibition of A9 and A10 dopamine neurons are 1.3 mg/kg and 0.5 mg/kg, respectively[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Rat α1 adrenoceptor | NRA-0160 | NRA0160 | NRA 0160 | DopamineReceptor | Dopamine Receptor | D4 Receptor | D3 Receptor | 5-HT2A Receptor |
| Inhibitors Related | Olanzapine | Clozapine N-Oxide | Mirtazapine | Octopamine hydrochloride | L-DOPA | Octodrine | Citicoline | Phenothiazine | Oxolinic acid | Mianserin hydrochloride | Doxepin hydrochloride | Fluphenazine dihydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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