Orexin A (human, rat, mouse) (acetate) NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-03 |
Product Details
| Product Name: Orexin A (human, rat, mouse) (acetate) | Supply Ability: 10g |
| Release date: 2025/09/03 |
Product Introduction
Bioactivity
| Name | Orexin A (human, rat, mouse) (acetate) |
| Description | Orexin A (human, rat, mouse) acetate (Hypocretin-1) is an excitatory neuropeptide with analgesic properties. It activates Orexin-1 (OX1R) and Orexin-2 (OX2R) receptors, used for studying neurodegenerative diseases. |
| In vitro | Orexin A (human, rat, mouse) acetate (0.1, 1, 10, 100 nM, 24h) increased the expression of BDNF in SH-SY5Y human dopaminergic neuroblastoma cells. [1] Orexin A (human, rat, mouse) acetate (5μM) therapy alleviated the decrease in the number of MC3T3-E1 cells and OCN expression induced by chronic intermittent hypoxia (CIH) by combining with OX1R. [2] |
| In vivo | Orexin A (human, rat, mouse) acetate(300 ng/ mouse, injected into the brain) significantly improved spatial learning and memory impairment in MPTP-induced Parkinson's disease mouse models. [1] Orexin A (human, rat, mouse) acetate treatment improved bone formation in CIH mice. [2] |
| Storage | keep away from moisture | Shipping with blue ice. |
| Solubility Information | H2O : 40 mg/mL (11.05 mM), Sonication is recommended. |
| Inhibitors Related | L-368,899 hydrochloride | YNT-185 | IPSU | MK-3697 | Filorexant | Suntinorexton | Orexin B, rat, mouse Acetate | OXA (17-33) acetate | PF3274167 | ACT-462206 | Seltorexant | TCS 1102 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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