Product Details
| Product Name:
Osocimab |
CAS No.:
2056878-75-0 |
| Purity:
> 95% |
Supply Ability:
10g |
| Release date:
2025/09/11 |
Product Introduction
Bioactivity
| Name | Osocimab |
| Description | Osocimab (BAY 1213790) is a potent anti-FXIa antibody with a Ki value of 2.4 nM and an EC50 value of 0.2 nM.Osocimab may reduce thrombosis through FXI inhibition.Osocimab is often used as an XI factor inhibitor, has an inhibitory effect on thrombin generation, has an anticoagulant effect, and is used in the study of thromboembolic diseases. Thromboembolic Diseases |
| In vitro | In human plasma, Osocimab (1.4 nM-1 μM; 30 min) demonstrated inhibition of thrombin production, as well as FXIa-mediated FIX activation (or FIX conversion) with an IC50 of 16 nM and FXIa-mediated substrate cleavage with an IC50 of 1.2 nM [1]. Osocimab, at a concentration of 22.05 mg/mL, inhibited activation of the intrinsic pathway-mediated coagulation cascade [1]. |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Osocimab | FXR | BAY-1213790 | BAY1213790 |
| Inhibitors Related | Forskolin | Ursodeoxycholic acid sodium | Altenusin | T0901317 | Obeticholic Acid | Lithocholic acid | Chenodeoxycholic acid | Sevelamer hydrochloride | Hyodeoxycholic acid | GSK2324 | Chenodeoxycholic Acid sodium salt | Fexaramine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States