Product Details
| Product Name: Osthole | CAS No.: 484-12-8 |
| Min. Order: 1ton | Purity: 99% |
| Supply Ability: 1000T/M | Release date: 2025/11/04 |
Technical Data Sheet (TDS)
Product Name: Osthole
Chemical Name: 7-Methoxy-8-(3-methyl-2-butenyl)coumarin
CAS No.: 484-12-8
Molecular Formula: C₁₅H₁₆O₃
Molecular Weight: 244.29
1. Product Description
Osthole is a natural coumarin compound extracted mainly from the fruits of Cnidium monnieri (L.) Cusson and other plants in the Umbelliferae family. It is a pale-yellow crystalline powder with a characteristic odor. Osthole is known for its wide range of biological activities and is used in both food and industrial applications.
2. Typical Specification
| Name of Index | Specification | Test Method |
|---|---|---|
| Appearance | Light yellow to off-white crystalline powder | Visual |
| Odor & Taste | Characteristic | Organoleptic |
| Mesh Size | 80–100 mesh | Sieve test |
| Moisture | ≤ 5.0% | GB/T 5009.3 |
| Ash | ≤ 5.0% | GB/T 5009.4 |
| Assay (Osthole, HPLC) | ≥ 98.0% | HPLC |
| Heavy Metals | ≤ 10 ppm | GB/T 5009.74 |
| Lead (Pb) | ≤ 2 ppm | ICP-MS |
| Arsenic (As) | ≤ 1 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
| Total Plate Count | ≤ 1000 CFU/g | GB 4789.2 |
| Yeast & Mold | ≤ 100 CFU/g | GB 4789.15 |
| E. coli | Negative | GB 4789.3 |
| Salmonella | Negative | GB 4789.4 |
3. Physical and Chemical Properties
Solubility: Insoluble in water; soluble in ethanol, ether, chloroform, and methanol.
Melting Point: 82–86°C
Stability: Stable under normal storage conditions; sensitive to strong light and heat.
Appearance: Crystalline powder with slight aromatic odor.
4. Applications
Food Grade Applications
Used as a functional ingredient in dietary supplements, nutraceuticals, and health foods.
Supports immune modulation, hormonal balance, and antioxidant activity.
Often included in traditional herbal formulas for general wellness.
Industrial Grade Applications
Used as an intermediate in the synthesis of pharmaceuticals, cosmetics, and bioactive materials.
Applied in anti-inflammatory creams, hair growth products, and antimicrobial formulations.
Serves as a natural pesticide component in eco-friendly agricultural applications.
5. Packaging & Storage
Packaging: 1kg/Aluminum foil bag, 25kg/Drum (inner double-layer PE bag).
Storage Conditions: Store in a cool, dry, and well-ventilated place. Keep away from direct sunlight and moisture.
Shelf Life: 24 months in unopened original packaging under proper conditions.
6. Safety & Handling
Handle in accordance with good industrial hygiene and safety practice.
Avoid inhalation of dust; use protective gloves and mask.
Non-toxic at recommended usage levels for food applications.
Refer to MSDS for detailed safety information.
7. Regulatory Status
Complies with GB, USP, and EP quality standards where applicable.
Food-grade Osthole is produced under GMP and ISO 9001 certified facilities.
Meets EU and FDA requirements for natural plant extract ingredients (for permitted uses).
8. Additional Information
Origin: Extracted from Cnidium monnieri (L.) Cusson.
Synonyms: Cnidimonin, Osthol, Snake-bed seed coumarin.
HS Code: 2932.21
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- Since: 2025-04-07
- Address: C-309, No. 12 Yuzhou S. Rd, Haizhou, Lianyungang, Jiangsu, China

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