PA452 NEW
| Price | $84 | $263 | $423 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-09 |
Product Details
| Product Name: PA452 | CAS No.: 457657-34-0 |
| Purity: 97.14% | Supply Ability: 10g |
| Release date: 2025/11/09 |
Product Introduction
Bioactivity
| Name | PA452 |
| Description | PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development. |
| In vitro | PA452 suppresses the Troglitazone (TZ)-induced CK13 expression. In normal human urothelial (NHU) cells, PA452 (0.01-1 μM) inhibits retinoic X receptor[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 4.4 mg/mL (10.01 mM), Sonication and heating are recommended. DMSO : 36 mg/mL (81.9 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.55 mM), Sonication is recommended. |
| Keywords | RXR | RetinoidReceptor | Retinoid Receptor | RAR/RXR | RAR | PA-452 | PA452 | PA 452 |
| Inhibitors Related | Isotretinoin | Adapalene | Oxybenzone | MSU-42011 | Tazarotene | Etodolac | ER 50891 | Acitretin | Tamibarotene | Bexarotene | TTNPB | K-8012 |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Cancer Cell Differentiation Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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