PD 404182 NEW
| Price | $32 | $75 | $113 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-04 |
Product Details
| Product Name: PD 404182 | CAS No.: 72596-74-8 |
| Purity: 99.20% | Supply Ability: 10g |
| Release date: 2025/11/04 |
Product Introduction
Bioactivity
| Name | PD 404182 |
| Description | PD 404182 is a human dimethylarginine dimethylaminohydrolase 1 (DDAH1) inhibitor with anti-angiogenic and antiviral activities, and can be used to study cardiovascular diseases and viral infections. |
| In vitro | The enzymatic activity of human DDAH1 was significantly and dose-dependently inhibited by PD 404182, with an IC50 = 9 μM. [1] PD 404182 exhibited antiviral activity toward all the viral isolates tested, with an average IC50 of 0.55 μM (IC50 range, 0.14 μM with HIV-1 96USNG31 to 1.18 μM with HIV-1 92UG029). A 48% reduction in cell viability was observed at the highest tested PD 404182 concentration (200 μM), resulting in a CC50 of ∼200 μM, indicating that PD 404182 is relatively nontoxic to freshly activated human PBMCs. [2] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (9.2 mM), Sonication is recommended. DMSO : 40 mg/mL (184.09 mM), Sonication is recommended. |
| Keywords | PD 404182 | DDAH1 |
| Inhibitors Related | Neomycin sulfate | Ampicillin sodium | Doxycycline (hyclate) | Kanamycin sulfate | Sulfacetamide sodium | Sulfamethoxazole sodium | Terbinafine hydrochloride | Metronidazole | Doxycycline | Penicillin G potassium | EDTA copper(II) disodium salt | Ampicillin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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