Product Details
| Product Name:
PP58 |
CAS No.:
212391-58-7 |
| Purity:
99.62% |
Supply Ability:
10g |
| Release date:
2026/07/27 |
Product Introduction
Bioactivity
| Name | PP58 |
| Description | PP58 is an inhibitor of PDGFR, FGFR and Src family. |
| In vitro | PP58 inhibits anisomycin-activated p38 in a dose-dependent manner with an IC50 < 10 nM. LPS-stimulated TNF-α production is potently inhibited by PP58 with a cellular IC50 value of 3 nM[1]. |
| In vivo | PP58 exhibits some degree of selectivity in vivo[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 56.3 mg/mL (123.38 mM), Sonication is recommended.
|
| Keywords | TNF-α | Src | PP-58 | PP58 | PP 58 | PDGFR | p38MAPK | p38 MAPK | p38 | FGFR |
| Inhibitors Related | Kaolin | Acetylcysteine | Gum arabic | Triphenyl phosphate | Fumaric acid | Sorafenib | 1,8-Cineole | Dodecane | Ferulic Acid | Tributyrin | Glucosamine | D-Psicose |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Cytokine Inhibitor Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Angiogenesis related Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | MAPK Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$34.00
|
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-07-27 |
United States