Protriptyline NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Protriptyline | CAS No.: 438-60-8 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Protriptyline |
| Description | Protriptyline is a potent antidepressant agent that inhibits AChE activity with an IC 50 value of 0.06 mM as well as inhibits Aβ Self-Assembly. Protriptyline has the potential to be used for depression and Alzheimer's disease [1] [2] [3]. |
| In vitro | Protriptyline (0-70 μM; 24 hours; PC3 cells) induces cytotoxicity in PC3 cells, decreasing cell viability in a concentration-dependent manner (50, 60, and 70 μM) [2]. |
| In vivo | Protriptyline (10 mg/kg; i.p.; for 21 days; rat model of AD) ameliorates spatial learning and retention memory in STZ-treated rats [3]. The treatment significantly reduced pTau, Aβ42, and BACE-1 levels, neurodegeneration, oxidative stress, and glial activation, while improving the p-ERK/ERK ratio, and enhancing BDNF and CREB levels by reducing NFκB and GFAP expression. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Benzenesulfonamide | Ethyl (triphenylphosphoranylidene) acetate | HEPPS | Diethyltoluamide | Rutin | 10-Undecenoic acid | 2,4-Di-tert-butylphenol | Dimethyl sulfoxide | Coumaran | Chlorzoxazone | Methyl tridecanoate | Trimethylammonium chloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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