Ratic
| Price | $280 |
| Package | 1KG |
| Min. Order: | 1KG |
| Update Time: | 2022-09-16 |
Product Details
| Product Name: Ratic | CAS No.: 66357-35-5 |
| EC-No.: 266-332-5 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: Ex 20 tons |
| Release date: 2022/09/16 |
| Description | Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Ranitidine is a weak inhibitor of CYP2C19 and CYP2C9[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Endocrinology Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Anti-infection >> Bacterial |
| Target | H2 Receptor:3.3 μM (IC50) CYP2C19 CYP2C9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature |
| SMILES | O=[N+](/C=C(NC)/NCCSCC1=CC=C(CN(C)C)O1)[O-] |
| References | [1]. A W Herling, et al. Inhibition of 14C-aminopyrine accumulation in isolated rabbit gastric glands by the H2-receptor antagonist HOE 760 (TZU-0460). Agents Actions. 1987 Feb;20(1-2):35-9. [2]. A Leucuta, et al. A pharmacokinetic interaction study between omeprazole and the H2-receptor antagonist ranitidine. Drug Metabol Drug Interact. 2004;20(4):273-81. [3]. Antonio Francesco Ciccaglione, et al. Pylera® plus ranitidine vs Pylera® plus esomeprazole in first-line treatment of Helicobacter pylori infection: Two pilot studies. Helicobacter. 2019 Oct;24(5):e12606. |
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