Product Details
| Product Name:
Remibrutinib |
CAS No.:
1787294-07-8 |
| Purity:
99.50% |
Supply Ability:
10g |
| Release date:
2025/07/30 |
Product Introduction
Bioactivity
| Name | Remibrutinib |
| Description | Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment. |
| In vitro | Remibrutinib inhibits Btk enzymatic activity (IC50: 1 nM in a biochemical enzyme assay). Remibrutinib inhibits Btk enzymatic activity in the blood (IC50: 0.023 μM in vitro B cell activation assay), the whole blood is collected from the abdominal aorta of anesthetized adult male Lewis rats[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (246.29 mM), Sonication is recommended.
|
| Keywords | Remibrutinib | Inhibitor | inhibit | BTK | Btk | Bruton tyrosine kinase |
| Inhibitors Related | evobrutinib | Acalabrutinib | Saracatinib | CP-547632 | BMS-986142 | Edralbrutinib | Ibrutinib | Branebrutinib | Orelabrutinib | Tirabrutinib hydrochloride | Pirtobrutinib | Rilzabrutinib |
| Related Compound Libraries | Highly Selective Inhibitor Library | Cysteine Covalent Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Drug Repurposing Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States