Resolvin E1 NEW
| Price | $1850 |
| Package | 50μg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-25 |
Product Details
| Product Name: Resolvin E1 | CAS No.: 552830-51-0 |
| Supply Ability: 10g | Release date: 2025/09/25 |
Product Introduction
Bioactivity
| Name | Resolvin E1 |
| Description | Resolvin E1 (RvE1) is an endogenous lipid mediator derived from the omega-3 fatty acid eicosapentaenoic acid (EPA). It exhibits anti-inflammatory properties, activates inflammation resolution, and promotes phagocytic clearance. It prevents 2,4,6-trinitrobenzenesulfonic acid-induced colitis and improves erythrocytosis and severe aplastic anaemia (SAA). |
| In vitro | Resolvin E1 specifically interacts with the LTB4 receptor BLT1 on neutrophils and ChemR23 on monocytes to regulate leukocytes during inflammation. Resolvin E1 also stimulates the uptake and clearance of local cytokine. Resolvin E1 (0.1-100 nM) gives concentration-dependent inhibition of TNF-α–induced NF-κB activation (EC50: ～1.0 nM in ChemR23-transfected cells). Resolvin E1 (100 nM) enhances phosphorylation of ERK mitogen-activated protein (MAP) kinase both in peripheral blood monocytes and HEK-ChemR23 cells [2][3]. |
| In vivo | Resolvin E1 (1.0 μg per mouse; 50 μg/kg; i.p.; on days -8, -1, and 0) protects mice from TNBS colitis[1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 40 mg/mL (114.14 mM), Sonication and heating are recommended. |
| Keywords | Resolvin E-1 | Resolvin E1 | Human Endogenous Metabolite |
| Inhibitors Related | Sucrose | Aceglutamide | Cysteamine hydrochloride | Urea | Levulinic acid | D(+)-Raffinose pentahydrate | Daidzein | Ferulic Acid | Glycerol | Thymidine | Sodium 2-hydroxybutanoate | 3-Indoleacetic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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