Ribocil-C Racemate NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-22 |
Product Details
| Product Name: Ribocil-C Racemate | CAS No.: 2309762-18-1 |
| Supply Ability: 10g | Release date: 2025/08/22 |
Product Introduction
Bioactivity
| Name | Ribocil-C Racemate |
| Description | Ribocil-C Racemate is the racemate of Ribocil-C, a highly selective inhibitor of bacterial riboflavin riboswitches that control the expression of de novo riboflavin (RF, vitamin B2) biosynthesis in Escherichia coli. |
| In vitro | Ribocil-C, a highly selective inhibitor of the flavin mononucleotide (FMN) riboswitch, effectively regulates the expression of de novo riboflavin (RF, vitamin B2) biosynthesis in Escherichia coli. It specifically targets dual FMN riboswitches to control both RF biosynthesis and uptake processes, critical for the growth and pathogenesis of Staphylococcus aureus. Additionally, Ribocil-C, a small-molecule synthetic FMN analog, binds the FMN riboswitch in various Gram-negative bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii. By inhibiting ribB expression and RF synthesis, it successfully halts bacterial proliferation [1] [2]. |
| In vivo | Treatment with higher doses of Ribocil-C (60 and 120 mg/kg) demonstrated a dose-dependent decrease in bacterial load, with reductions of 1.87 and 3.29 log10 [CFU per g spleen], respectively, compared to the sham-treated mice. No mortality or significant toxicity effects were observed [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 30 mg/mL (71.51 mM), Sonication is recommended. |
| Keywords | Ribocil-C Racemate | RibocilC Racemate | Ribocil C Racemate | Bacterial riboflavin riboswitches |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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