Product Details
| Product Name:
Rilotumumab |
CAS No.:
872514-65-3 |
| Purity:
97.51% (SEC-HPLC) |
Supply Ability:
10g |
| Release date:
2025/10/19 |
Product Introduction
Bioactivity
| Name | Rilotumumab |
| Description | Rilotumumab (AMG 102) is a monoclonal antibody targeting hepatocyte growth factor that inhibits HGF/ MET-driven signaling. Rilotumumab has antitumor effects and can be used to study castration-resistant prostate cancer (CRPC) and gastric cancer. |
| In vitro | In an overnight treatment at 10 μg/mL, Rilotumumab induces a decrease in MET phosphorylation at Y1234 and Y1235, accompanied by an increase in total MET[2]. |
| In vivo | In vivo, treatment with Rilotumumab (intraperitoneal injection; 1.5 mg/kg; once every two days; for 11 days) inhibits glioma cell growth[2]. |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Rilotumumab | HGFR | c-Met/HGFR | cMet/HGFR | c-Met | cMet | AMG-102 | AMG102 |
| Inhibitors Related | Cabozantinib | BMS-754807 | Capmatinib 2HCl | (±)-Norcantharidin | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | Tepotinib | Amuvatinib | Norcantharidin | AMG-458 | Cabozantinib S-malate | Capmatinib xHCl |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States