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Postion:Product Catalog >API>Nervous system drugs>Drug Metabolism in Human Brain>Rivastigmine
Rivastigmine
  • Rivastigmine

Rivastigmine NEW

Price $47 $55 $81
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-09

Product Details

Product Name: Rivastigmine CAS No.: 123441-03-2
Purity: 99.85% Supply Ability: 10g
Release date: 2025/06/09

Product Introduction

Bioactivity

NameRivastigmine
DescriptionRivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
Cell ResearchChronic toxicity is assessed 7 days after continuous exposure of cells to donepezil or rivastigmine using cell viability and cell esterase activity and the estimated cell numbers as parameters for viability. Culture medium including the tested drugs is changed once after 4 days.(Only for Reference)
In vivoPreclinical biochemical studies indicates that rivastigmine has central nervous system selectivity over peripheral inhibition. It ameliorates memory impairment in rats with forebrain lesions. The drug is rapidly absorbed orally, with a bioavailability of 0.355 and low protein binding (40%). Its elimination halflife is less than 2 hours, and it is converted to an inactive metabolite at the site of action, bypassing hepatic metabolic pathways. Its disposition essentially is unaltered in patients with renal or hepatic impairment. It also has dosedependent effects on AChE inhibition[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 70 mg/mL (279.62 mM), Sonication is recommended.
KeywordsSDZ-ENA-713 | SDZ-ENA713 | Rivastigmine | Parkinson's | parasympathomimetic | orally | Inhibitor | inhibit | disease | Cholinesterase (ChE) | cholinesterase | cholinergic | ChE | butyrylcholinesterase | BChE | BBB | Alzheimer's | AChE | acetylcholinesteras
Inhibitors Related1-Naphthyl acetate | DL-Menthol | Ethyl (triphenylphosphoranylidene) acetate | 4-Methylbenzylidene camphor | Isoeugenol acetate | Diethyltoluamide | sn-Glycero-3-phosphocholine | Nizatidine | Coumaran | Methyl tridecanoate | Trimethylammonium chloride | Trimyristin
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pediatric Drug Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Orally Active Compound Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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