Saterinone NEW
| Price | $67 | $163 | $247 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-24 |
Product Details
| Product Name: Saterinone | CAS No.: 102669-89-6 |
| Purity: 98.23% | Supply Ability: 10g |
| Release date: 2025/10/24 |
Product Introduction
Bioactivity
| Name | Saterinone |
| Description | Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic heart failure. Saterinone inhibited crude cAMP phosphodiesterase (PDE) activity in guinea pig right ventricular homogenates The ic50 value is 2.3 × 10(-5) mol/l. |
| In vitro | Saterinone selectively and potently inhibited the isoenzyme III of PDE (IC50 = 0.06 mumol/l). Thus, saterinone proved to be a selective inhibitor of 'low-Km, cAMP specific' PDE III.[1] |
| In vivo | Saterinone (1-30 mumol/l) exerted a concentration-dependent positive inotropic effect (EC50 = 9.1 mumol/l) in guinea pig papillary muscles.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 4.75 mg/mL (10.01 mM), Sonication is recommended. |
| Keywords | α1-adrenoceptor | Phosphodiesterase (PDE) | AdrenergicReceptor | Adrenergic Receptor |
| Inhibitors Related | Theophylline monohydrate | Octopamine hydrochloride | Dexmedetomidine hydrochloride | Theobromine | Apremilast | Amitriptyline hydrochloride | Indomethacin | Icariin | Trazodone hydrochloride | Mianserin hydrochloride | Doxofylline | Sildenafil citrate |
| Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Cardiovascular Disease Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Adrenergic Receptor-Targeted Compound Library | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2500.00/100mg |
VIP2Y
|
TargetMol Chemicals Inc.
|
2025-08-21 | |
| $2500.00/100mg |
VIP4Y
|
TargetMol Chemicals Inc.
|
2025-08-21 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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