Slingshot inhibitor D3 NEW
| Price | $35 | $59 | $94 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-10 |
Product Details
| Product Name: Slingshot inhibitor D3 | CAS No.: 1715076-35-9 |
| Purity: 99.53% | Supply Ability: 10g |
| Release date: 2025/11/10 |
Product Introduction
Bioactivity
| Name | Slingshot inhibitor D3 |
| Description | Slingshot inhibitor D3 (JHN76359) is a potent inhibitor of the Protein Phosphatase Slingshot. |
| In vitro | Slingshot 1 had?IC50?value of 3 μM and Slingshot 2 had?Ki value of 3.9 μM.?Slingshot inhibitor D3 has similar inhibitory activitieswith Slingshot 1 and Slingshot 2. |
| In vivo | Slingshot inhibitor D3 (5 μM; 45 minutes; PC12 cells;) significantly blocks NGF-induced dephosphorylation of cofilin at 15 and 30 minutes. Slingshot inhibitor D3 (5 μM; 45 minutes; PC12 cells) significantly decreases the NGF-induced cell migration, consistent with its inhibitory role in cofilin dephosphorylation. Slingshot inhibitor D3 (HEK293 cells) specifically blocks angiotensin II-induced cofilin dephosphorylation. Slingshot inhibitor D3 prevents cofilin dephosphroylation through inhibition of Slingshot. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 23.08 mg/mL (50 mM), Sonication and heating to 60℃ are recommended. |
| Keywords | Slingshot inhibitor D-3 | Slingshot inhibitor D3 | Slingshot inhibitor D 3 | Slingshot 2 | Slingshot 1 | selective | reversible | potent | PC12 | JHN-76359 | JHN 76359 | Inhibitor | inhibit | HEK293 | competitive |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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