Product Details
| Product Name:
Sovesudil |
CAS No.:
1333400-14-8 |
| Supply Ability:
10g |
Release date:
2025/08/21 |
Product Introduction
Bioactivity
| Name | Sovesudil |
| Description | Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor, showing IC50 values of 3.7 nM for ROCK-I and 2.3 nM for ROCK-II, and capable of lowering intraocular pressure (IOP) without inducing hyperemia. |
| In vitro | Sovesudil (PHP-201) at a concentration of 1 μM, when administered for 60 minutes, can induce changes in the behavior of human trabecular meshwork (HTM) cells [1]. |
| In vivo | Sovesudil, at concentrations of 0.1%, 0.3%, and 0.5%, administered to male New Zealand White rabbits, effectively lowers Intraocular Pressure (IOP) in both normotensive and acute hypertensive conditions without inducing significant hyperemia [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States