Spermidine NEW

Spermidine

Bulk supplier | spermidine free base; 1,5,10-triazadecane | CAS 124-20-9 | polyamine metabolite | pathgene

Spermidine is a naturally occurring triamine and polyamine metabolite. CAS 124-20-9 identifies the free-base form with formula C7H19N3 and molecular weight 145.25 g/mol. It is used in analytical and formulation development, polyamine research and ingredient screening where the free base, rather than a hydrochloride salt, is the required chemical form.

Free base or salt

The free base is relevant to studies that calculate spermidine on a free-base basis or need a liquid material for dilution and analytical preparation. The reviewed COA describes a colorless liquid and includes anhydrous assay, methanol residue and trace-metal fields, which are useful when building a solution or dosing calculation.

Why it fits: Spermidine is a polycationic amine that interacts with acidic biomolecules; its apparent behavior changes with pH and counterion. That is why a free-base record should not be merged with spermidine trihydrochloride, even though both supply the same parent polyamine.

Product distinction

The free base is 145.25 g/mol, while spermidine trihydrochloride is 254.63 g/mol and is a water-soluble solid. A customer targeting 10 mg of spermidine itself must use the active-basis calculation and not the salt mass without accounting for the three hydrochloride equivalents.

Technical selection points

·        The reviewed COA records MS identification consistent with the structure.

·        Purity was 99.3% and dry-basis assay was 99.1% in the reviewed batch.

·        The COA reports a colorless liquid, water ≤0.5% and methanol not detected.

Selection note: State free base versus trihydrochloride, active-basis calculation, solution concentration and intended use in the RFQ. Reconcile the controlled batch record before using production date or expiry claims in a release decision.

Product identity

Documented batch evidence

The figures below are from pathgene COA PGSPD-260611 and describe one historical lot. They are not a blanket specification for every future shipment.

Batch PGSPD-260611; Production and test dates are recorded on the batch COA; verify against the controlled batch record. Pack recorded for this lot: 10 kg/drum. Storage statement: tightly stoppered, dark, 2-8°C.

Application boundary

Research findings and chemical function explain why this material may fit a development program; they do not establish a treatment effect, a recommended human dose or government approval. Finished-product suitability remains dependent on the intended market and formulation.

References

·        PubChem Spermidine: https://pubchem.ncbi.nlm.nih.gov/compound/124-20-9

·        CAS Common Chemistry record via PubChem: https://commonchemistry.cas.org/detail?cas_rn=124-20-9

·        pathgene ingredient catalog: https://pathgenebio.com/en/ingredients/nutrition-functional

For sample and quotation discussions, provide the CAS, intended use, target quantity and required documentation. pathgene website