![Sulfonium, [4-(1,1-dimethylethyl)phenyl]diphenyl-, 7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate (1:1)](/ProductImageEN1/2025-06/Large/5011d8a0-731d-4aa2-9d32-14c1ac803bcb.png)
![Sulfonium, [4-(1,1-dimethylethyl)phenyl]diphenyl-, 7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate (1:1)](/ProductImageEN1/2025-06/Small/5011d8a0-731d-4aa2-9d32-14c1ac803bcb.png)
Product Details
| Product Name: Sulfonium, [4-(1,1-dimethylethyl)phenyl]diphenyl-, 7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate (1:1) | CAS No.: 186769-11-9 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 100kg | Release date: 2025/10/13 |
| Lead time: in stock | Packaging: bag/bottle/drum//IBC, as request |
| Delivery: By sea, by air, by express | Origin: Manufacturer, advantage products |
| COA, MSDS: Available, contact us for details | Contact: Tina |
PRODUCT INFORMATION
| Name | Vutrisiran |
|---|
| Description | Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR)-mediated amyloidosis research[1]. |
|---|---|
| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease |
| In Vitro | Vutrisiran (previously ALN-TTRSC02) is a second-generation investigational RNAi therapeutic under development for the study of ATTR amyloidosis. Vutrisiran contains an siRNA that targets a sequence within the TTR mRNA which is conserved across wt and all known TTR variants. However, the Vutrisiran siRNA utilizes enhanced stabilization chemistry (ESC) and is conjugated to a triantennary GalNAc ligand, with the aim of enabling infrequent, subcutaneous (SC) dosing[1]. |
| In Vivo | In non-human primates, single SC doses of Vutrisiran 0.3 and 1 mg/kg achieved mean maximum TTR reductions (nadirs) of 55% and 96%, respectively, with serum TTR reductions persisting beyond 4 months for the 1 mg/kg dose. In the same study, monthly doses of 1 and 3 mg/kg maintained a reduction of TTR levels at 96%, relative to baseline[1]. |
| References | [1]. Bahru A Habtemariam, et al. Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects. Clin Pharmacol Ther. 2021 Feb;109(2):372-382. |
| No Any Chemical & Physical Properties |
Company Profile
Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.
Our Company
Our Advantage
Rich experience
Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.
Excellent quality, purity, and competitive price
Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.
Safe and fast delivery
We will arrange shipment of spot products as soon as we receive payment.
Customized products are determined based on the synthesis time of different products.
Excellent pre-sales and after-sales service
Pre sales:
We are committed to providing the most favorable quotes and detailed information about our products and company.
after-sale service:
We assist buyers in customs clearance by providing necessary documents and information.
If there is any dispute over product quality, we are committed to providing the best solution.
• Packaging:
1kg/bag, 25kg/drum, 50kg/drum, 180kg/drum, 200kg/drum, 1T/bag/drum, standard export packaging or packaging required by customers
• Shipping
• Delivery:
Within 7 days after receiving your payment
Contact information
For more details, pls contact us freely.
Contact name: Tina
Email address: Tina@fdachem.com
Mob: 86 13213167925
WhatsApp/Skype/Wechat/LINE: 86 15225627621
Company Profile Introduction
You may like
-
![Sulfonium, [4-(1,1-dimethylethyl)phenyl]diphenyl-, salt with 2,2-difluoro-2-sulfo-1-(trifluoromethyl)ethyl 4-oxotricyclo[3.3.1.13,7]decane-1-carboxylate (1:1)](https://img.chemicalbook.com/ProductImageEN1/2025-06/Large/54fa502b-06f3-4bbe-89d1-5f62e9f97371.png)
-
![Sulfonium, [4-(1,1-dimethylethyl)phenyl]diphenyl-, salt with 1-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)methyl] 2,2-difluoro-2-sulfoacetate](https://img.chemicalbook.com/ProductImageEN1/2025-06/Large/da85461d-4088-4580-978b-e050a6a2d5f6.png)
-
![DIPHENYL[4-(PHENYLTHIO)PHENYL]SULFONIUM, TRIFLUOROTRIS(1,1,2,2,2-PENTAFLUOROETHYL)PHOSPHATE(1-) (1:1](https://img.chemicalbook.com/ProductImageEN1/2025-07/Large/501783ac-0b74-49f5-b92c-a60527b6e6d6.png)
DIPHENYL[4-(PHENYLTHIO)PHENYL]SULFONIUM, TRIFLUOROTRIS(1,1,2,2,2-PENTAFLUOROETHYL)PHOSPHATE(1-) (1:1CAS:870681-07-5
$2.00 / 25KG
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/1G/KG |
VIP2Y
|
Anhuyan (Hainan) Biotechnology Co., LTD
|
2025-02-12 | |
| $0.00/25KG |
VIP2Y
|
Shaanxi Dideu New Materials Co. Ltd
|
2025-05-19 | |
| $6.00/1kg |
VIP2Y
|
Henan Fengda Chemical Co., Ltd
|
2024-04-22 |
China