Product Details
| Product Name:
TAK-779 |
CAS No.:
229005-80-5 |
| Purity:
99.21% |
Supply Ability:
10g |
| Release date:
2025/04/29 |
Product Introduction
Bioactivity
| Name | TAK-779 |
| Description | TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3). |
| In vitro | TAK-779 (250 mg/animal per day) inhibits ovalbumin-induced increases in CCR5, CXCR3, IFN-γ, and TNF-α expression in mouse lung, as well as the number of total cells, lymphocytes, and eosinophils in bronchoalveolar lavage fluid (BALF), in a mouse model of asthma[1]. |
| In vivo | TAK-779 increases intestinal allograft survival in a rat model of small intestine transplantation when administered at a dose of 10 mg/kg per day[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 16.66 mg/mL (31.37 mM), Sonication is recommended.
DMSO : 25 mg/mL (47.07 mM), Sonication is recommended.
|
| Keywords | Takeda-779 | Takeda779 | TAK-779 | TAK779 | TAK 779 | Inhibitor | inhibit | Human immunodeficiency virus | HIVProtease | HIV Protease | HIV | CXCR | CXC chemokine receptors | CCR2 | CCR | CC chemokine receptor |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Kaempferol | Dolutegravir intermediate-1 | Tannic acid | Dextran sulfate sodium salt (MW 4500-5500) | Lamivudine | Chloroquine phosphate | Valproic Acid | Decanedioic acid | Tenofovir |
| Related Compound Libraries | Bioactive Compound Library | Cytokine Inhibitor Library | Membrane Protein-targeted Compound Library | Anti-Viral Compound Library | Inhibitor Library | Immuno-Oncology Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | GPCR Compound Library | Anti-COVID-19 Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$/ |
VIP5Y
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RongNa Biotechnology Co.,Ltd
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2025-04-29 |
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$0.00/1g |
VIP1Y
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Xi an Biohorlden Industry Trade Co Ltd
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2025-04-17 |
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$80.00/1kg |
VIP2Y
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Zibo Hangyu Biotechnology Development Co., Ltd
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2023-10-30 |
United States