Tallimustine HCl NEW
| Price | $195 | $430 | $636 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-13 |
Product Details
| Product Name: Tallimustine HCl | CAS No.: 118438-45-2 |
| Purity: 98.52% | Supply Ability: 10g |
| Release date: 2025/09/13 |
Product Introduction
Bioactivity
| Name | Tallimustine HCl |
| Description | Tallimustine HCl is a DNA inhibitor, an AT-specific alkylated antitumor derivative of diamycin.Tallimustine HCl can be used in severe combined immunodeficiency mouse models of adult myelogenous leukemia, which can be used for the treatment of leukemia. |
| In vitro | Tallimustine HCl (0.1-10 μM; 4 h) causes harm to isolated SV40 DNA. Additionally, Tallimustine HCl exhibits cytotoxicity in CEM cells after 72 hours, displaying an IC50 of 3.5 nM.[1] Tallimustine HCl (25 and 100 nM, 6 days) induces erythroid differentiation of K562 cells.[2] Tallimustine HCl (100 nM, 6 days) increases accumulation of γ-globin mRNA in K562 cells.[2] Tallimustine HCl (0.5 μg/mL, 1 h) arrests SW626 cells in G2/M phase.[3] |
| In vivo | Tallimustine HCl (3 mg/kg; i.p.; ) prolonged survival and shows antileukemic activity in L1210 tumor-bearing mice and.[4] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 45 mg/mL (61.3 mM), Sonication is recommended. |
| Keywords | Tallimustine HCl | DNA |
| Inhibitors Related | Norharmane | Cyclophosphamide hydrate | Quinacrine dihydrochloride | Elinafide | Clofazimine | L82 | Proflavine Hemisulfate | Chromium picolinate | Hydroxychloroquine sulfate | Methoxsalen | Cyclophosphamide | Crystal Violet |
| Related Compound Libraries | DNA Damage & Repair Compound Library | Bioactive Compound Library | Hematonosis Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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