VRT-325 NEW
| Price | $350 | $970 | $1200 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: VRT-325 | CAS No.: 815592-21-3 |
| Purity: 99.58% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | VRT-325 |
| Description | VRT-325 is a CFTR modulator with the ability to promote ΔF508-CFTR folding and endoplasmic reticulum trafficking. VRT-325 restores chloride transport in bronchial epithelial cells from cystic fibrosis patients and accelerates healing of CF cell monolayers, used for experimental research in cystic fibrosis. |
| In vitro | Methods: BHK cells were treated with approximately 2 μM VRT-325, and CFTR protein maturation was assessed by Western blot. Results: VRT-325 significantly promoted Delta F508-CFTR maturation and membrane expression, with enhanced efficacy when combined with Corr-2b.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (244.79 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2.63 mg/mL (5.15 mM), Solution. 10% DMSO+90% Saline : < 2.63 mg/mL (5.15 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| Keywords | VRT534 | VRT-325 | VRT 534 | CF106951 | CF 106951 |
| Inhibitors Related | Glibenclamide | CFTR corrector 8 | Lumacaftor | VRT-532 | GLPG1837 | Glucosamine | CFTR corrector 4 | Corrector C4 | Ataluren | DNDS | Glafenine | BPO-27 racemate |
| Related Compound Libraries | Bioactive Compound Library | ReFRAME Related Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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