VEGF120产品信息
英文名称:Vascular endothelial growth factor A
中文名称:血管内皮生长因子A
靶点别称:VEGF120,VEGFA
物种:Mouse
标签:Tag Free/His Tag & Avi Tag
属性:Protein
标记:Biotin-labeled/Unconjugated
表达区间及表达系统(Source)
Mouse VEGF120 Protein, Tag Free (VE0-M4211) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 146 (Accession # AAB22254.1 ).
Predicted N-terminus: Ala 27
蛋白结构(Molecular Characterization)

This protein carries no "tag".
The protein has a calculated MW of 14.1 kDa. The protein migrates as 18-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
无菌(Sterility)
Negative
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
血管内皮生长因子A(VEGFA)也称为血管通透性因子(VPF)。VEGFA属于PDGF/VEGF生长因子家族。VEGFA是一种糖基化丝裂原,特异性作用于内皮细胞,具有多种作用,包括介导血管通透性增加、诱导血管生成、血管生成和内皮细胞生长、促进细胞迁移和抑制凋亡。或者,编码自由分泌或细胞相关异构体的剪接转录变体已被表征。由于选择性剪接,VEGFA由一组三种主要亚型产生,如果产生任何三种亚型(VEGFA120、VEGFA164和VEGFA188),则不会导致小鼠血管缺陷和完全VEGFA敲除死亡。
关键字: VEGFA;VEGFA蛋白;VEGF120重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。