SOX1抗体,Rabbit Polyclonal SOX1 Antibody
  • SOX1抗体,Rabbit Polyclonal SOX1 Antibody
  • SOX1抗体,Rabbit Polyclonal SOX1 Antibody
  • SOX1抗体,Rabbit Polyclonal SOX1 Antibody

Rabbit Polyclonal SOX1 Antibody

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-09
QQ交谈 微信洽谈

产品详情

中文名称:SOX1抗体英文名称:Rabbit Polyclonal SOX1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 114 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: SOX1
2025-05-09 SOX1抗体 Rabbit Polyclonal SOX1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 114 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

产品详情

WB Predicted band size39 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human SOX1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human liver cancer tissue, 293T cells, Primary antibody: P04207(SOX1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


           

参考文献

以下是3篇与SOX1抗体相关的文献信息及摘要概括:

1. **文献名称**:*SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome*

**作者**:Sabater L, Titulaer M, Saiz A, et al.

**摘要**:该研究首次发现SOX1抗体可作为副肿瘤性Lambert-Eaton肌无力综合征(LEMS)的生物标志物,尤其在合并小细胞肺癌的患者中阳性率显著,提示其潜在的肿瘤筛查价值。

2. **文献名称**:*SOX1 autoantibodies in patients with paraneoplastic neurological syndromes*

**作者**:Titulaer MJ, Klooster R, Potman M, et al.

**摘要**:通过分析副肿瘤性神经综合征(PNS)患者血清,发现SOX1抗体与肺癌(尤其是小细胞肺癌)相关神经综合征高度相关,建议将其作为肺癌筛查的辅助指标。

3. **文献名称**:*Antibodies to SOX1 and other neuronal antigens in paraneoplastic disorders*

**作者**:Gultekin SH, Dalmau J, Graus Y, et al.

**摘要**:研究揭示了SOX1抗体在副肿瘤性疾病中的特异性表达模式,强调其与Huwey综合征及神经母细胞瘤的关联,并探讨其可能的致病机制。

如需具体研究细节或更多文献,可进一步补充说明需求。

       

背景信息

SOX1 antibodies are autoantibodies targeting SOX1. a member of the SOX (SRY-related HMG-box) family of transcription factors. SOX1 plays a critical role in early neurogenesis, particularly in the development and maintenance of neural progenitor cells within the central nervous system. It regulates the differentiation of neurons and glial cells, with expression predominantly observed in the embryonic neural tube and adult neural tissues.

Clinically, SOX1 antibodies are recognized as biomarkers for paraneoplastic neurological syndromes (PNS), especially in association with small cell lung cancer (SCLC). Their presence is strongly linked to Lambert-Eaton myasthenic syndrome (LEMS) and paraneoplastic cerebellar degeneration (PCD). Detection of SOX1 antibodies aids in distinguishing paraneoplastic from non-paraneoplastic neurological disorders, enhancing diagnostic accuracy. While not exclusive to malignancy, their high specificity for SCLC (reported in ~60-70% of LEMS cases) underscores their utility in prompting oncological evaluation.

Testing typically involves indirect immunofluorescence or immunoblot assays using recombinant SOX1 proteins. However, interpretation requires correlation with clinical context, as SOX1 antibodies may coexist with other onconeural antibodies (e.g., anti-Hu, anti-Yo). Research continues to explore their pathogenic role, though current evidence suggests they may serve as epiphenomena rather than direct contributors to neurological damage. Their identification remains a key component in the diagnostic workup of autoimmune neurological disorders with suspected paraneoplastic etiology.

       
关键字: SOX1抗体;SOX1;SOX1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

店内推荐

Rabbit Polyclonal SOX1 Antibody相关厂家报价

更多
产品名称 价格   公司名称 报价日期
¥1138
VIP4年
上海沪震实业有限公司
2026-01-07
¥1800
VIP5年
上海雅吉生物科技有限公司
2025-12-04
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
询价
湖北艾普蒂生物工程有限公司
2024-02-21
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.