B3GAT1抗体,Mouse Monoclonal B3GAT1 Antibody
  • B3GAT1抗体,Mouse Monoclonal B3GAT1 Antibody
  • B3GAT1抗体,Mouse Monoclonal B3GAT1 Antibody
  • B3GAT1抗体,Mouse Monoclonal B3GAT1 Antibody

B3GAT1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-10
QQ交谈 微信洽谈

产品详情

中文名称:B3GAT1抗体英文名称:Mouse Monoclonal B3GAT1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 879 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Mouse
偶联物: 靶点: B3GAT1
2025-05-10 B3GAT1抗体 Mouse Monoclonal B3GAT1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 879 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM1/200 - 1/400 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

产品详情

AliasesNK1; CD57; HNK1; LEU7; NK-1; GLCATP; GLCUATP
Entrez GeneID27087
clone3B8B10
WB Predicted band size38.2kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human B3GAT1 (AA: 193-334) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

+ +

  •  

     

       Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    


  •  

     

       Western blot analysis using B3GAT1 mouse mAb against MOLT4 (1), Raji (2), and Ramos (3) cell lysate.    


  •  

     

       Flow cytometric analysis of Hela cells using B3GAT1 mouse mAb (green) and negative control (red).    


           

参考文献

以下是关于B3GAT1抗体的3篇参考文献的简要信息(文献名称、作者及摘要内容概括):

---

1. **文献名称**: "B3GAT1 modulates β1 integrin-dependent glioblastoma cell adhesion by regulating HNK-1 carbohydrate biosynthesis"

**作者**: Yamamoto S, et al.

**摘要**: 研究揭示了B3GAT1通过合成HNK-1糖表位调控β1整合素介导的胶质母细胞瘤细胞黏附,抗体被用于Western blot和免疫荧光实验验证B3GAT1的表达及其与肿瘤侵袭性的关联。

---

2. **文献名称**: "Antibody-based detection of B3GAT1 in human pluripotent stem cell-derived neurons"

**作者**: Smith J, et al.

**摘要**: 通过B3GAT1抗体(免疫组化及流式细胞术)证实该酶在人诱导多能干细胞分化的神经元中表达,提示其在神经发育及突触功能中的作用,抗体特异性经敲除细胞系验证。

---

3. **文献名称**: "B3GAT1 as a potential biomarker in ovarian cancer: Immunohistochemical analysis using a novel monoclonal antibody"

**作者**: Chen L, et al.

**摘要**: 开发了一种针对B3GAT1的单克隆抗体,通过免疫组化分析卵巢癌组织,发现其高表达与患者不良预后相关,抗体特异性通过siRNA敲降实验验证。

---

**备注**:以上文献为示例,实际文献需通过PubMed、Google Scholar等平台检索确认。若需具体论文,可补充提供DOI或PMID进一步查询。

       

背景信息

The B3GAT1 antibody targets the β-1.3-glucuronyltransferase 1 (B3GAT1) enzyme, also known as GlcAT-I, which plays a critical role in glycosaminoglycan (GAG) biosynthesis. This enzyme catalyzes the transfer of glucuronic acid to the terminal galactose residue in the linker region of proteoglycans, a step essential for forming the carbohydrate-protein linkage required for heparan sulfate and chondroitin sulfate chains. These glycosylated structures are vital for cellular processes, including cell adhesion, neural development, and extracellular matrix organization. B3GAT1 is particularly notable for its involvement in the biosynthesis of HNK-1 (human natural killer-1) carbohydrate epitopes, which are implicated in synaptic plasticity, memory formation, and immune cell interactions. Dysregulation of B3GAT1 has been associated with neurodevelopmental disorders, connective tissue abnormalities, and tumor progression. Antibodies against B3GAT1 are widely used in research to investigate its expression patterns, enzymatic activity, and functional roles in both normal physiology and disease models. They enable applications such as Western blotting, immunohistochemistry, and flow cytometry, aiding in the study of glycosylation defects and potential therapeutic targets. Recent studies also explore its interaction with integrins and growth factor receptors, highlighting its broader impact on cellular signaling pathways.
       
关键字: B3GAT1抗体;B3GAT1;B3GAT1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

店内推荐

B3GAT1抗体相关厂家报价

产品名称 价格   公司名称 报价日期
¥1098
VIP4年
上海沪震实业有限公司
2026-06-01
¥960.00
VIP10年
北京索莱宝科技有限公司
2026-05-28
询价
VIP4年
维百奥(北京)生物科技有限公司
2026-05-28
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.