CTSV抗体,Rabbit Polyclonal CTSV Antibody
  • CTSV抗体,Rabbit Polyclonal CTSV Antibody
  • CTSV抗体,Rabbit Polyclonal CTSV Antibody
  • CTSV抗体,Rabbit Polyclonal CTSV Antibody

CTSV抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
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产品详情

中文名称:CTSV抗体英文名称:Rabbit Polyclonal CTSV Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1639 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CTSV
2025-05-11 CTSV抗体 Rabbit Polyclonal CTSV Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1639 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/500-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesCTSU; CATL2; CTSL2
WB Predicted band size37 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human CTSV
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Jurkat cell, Mouse placenta tissue lysates, Primary antibody: P00239(CTSV Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00239(CTSV Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P00239(CTSV Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于CTSV抗体的3篇参考文献示例(注:以下内容为模拟生成,实际文献需通过学术数据库查询):

1. **文献名称**:*"Development of a Monoclonal Antibody Specific for Cathepsin V and Its Application in Immunohistochemical Analysis"*

**作者**:Johnson, R. et al.

**摘要**:该研究开发了一种针对CTSV(组织蛋白酶V)的高特异性单克隆抗体,验证了其在免疫组织化学(IHC)中的应用。实验表明,该抗体能有效区分CTSV与同源蛋白CTSL,并在卵巢癌组织中检测到CTSV的异常高表达。

2. **文献名称**:*"Cathepsin V as a Prognostic Biomarker in Triple-Negative Breast Cancer: Insights from Antibody-Based Detection"*

**作者**:Lee, S. & Martinez, A.

**摘要**:通过抗CTSV抗体进行Western blot和免疫荧光分析,研究发现CTSV在三阴性乳腺癌(TNBC)中显著上调,其表达水平与患者生存率负相关,提示其作为预后标志物的潜力。

3. **文献名称**:*"Structural Characterization of Cathepsin V Using Antibody Epitope Mapping"*

**作者**:Zhang, Y. et al.

**摘要**:利用抗CTSV抗体的表位定位技术,解析了CTSV的关键功能结构域,揭示了其底物结合特异性机制,为开发靶向CTSV的抑制剂提供了结构学依据。

**提示**:实际研究中建议通过PubMed、Web of Science等平台,以关键词“CTSV antibody”、“Cathepsin V antibody”或结合具体应用(如“CTSV cancer biomarker”)检索最新文献。

       

背景信息

The CTSV antibody targets Cathepsin V (CTSV), a lysosomal cysteine protease belonging to the papain-like protease family. Also known as Cathepsin L2. CTSV shares structural and functional similarities with Cathepsin L but exhibits distinct substrate specificity and tissue expression patterns. It is primarily expressed in thymic epithelial cells, corneal epithelium, and certain immune cells, playing roles in antigen processing, extracellular matrix remodeling, and cellular homeostasis. CTSV is synthesized as an inactive proenzyme that undergoes proteolytic cleavage in acidic environments to become an active protease.

Research highlights CTSV's involvement in pathological conditions, including cancer, autoimmune disorders, and inflammatory diseases. Overexpression of CTSV has been observed in melanoma, breast cancer, and rheumatoid arthritis, where it contributes to tissue invasion, metastasis, and chronic inflammation by degrading collagen and other structural proteins. CTSV antibodies are vital tools for detecting its expression and localization in tissues or cell cultures, facilitating studies on its biological functions and disease associations. These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and flow cytometry. Additionally, CTSV is explored as a potential therapeutic target, with inhibitors under investigation for modulating its activity in disease contexts. Its dual role in physiological processes and pathology makes CTSV a compelling subject for biomedical research.

       
关键字: CTSV抗体;CTSV;CTSV Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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