GALK1抗体,Rabbit Polyclonal GALK1 Antibody
  • GALK1抗体,Rabbit Polyclonal GALK1 Antibody
  • GALK1抗体,Rabbit Polyclonal GALK1 Antibody
  • GALK1抗体,Rabbit Polyclonal GALK1 Antibody

GALK1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
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产品详情

中文名称:GALK1抗体英文名称:Rabbit Polyclonal GALK1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1944 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: GALK1
2025-05-11 GALK1抗体 Rabbit Polyclonal GALK1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1944 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesGK1; GALK; HEL-S-19
WB Predicted band size42 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human GALK1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: P01395(GALK1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P01395(GALK1 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain  tissue using P01395(GALK1 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于GALK1抗体的3篇参考文献(文献为模拟示例,实际需根据真实数据库查询):

1. **文献名称**:*"Characterization of a Novel Monoclonal Antibody Against Human Galactokinase 1 (GALK1) and Its Application in Metabolic Disorder Studies"*

**作者**:Smith A, et al.

**摘要**:该研究开发了一种高特异性抗GALK1单克隆抗体,验证了其在Western blot和免疫组化中的应用,并探讨了GALK1在半乳糖代谢异常患者组织中的表达变化。

2. **文献名称**:*"Structural Insights into GALK1 Dysfunction in Galactosemia via Epitope-Specific Antibody Mapping"*

**作者**:Chen L, et al.

**摘要**:通过表位特异性抗体定位技术,揭示了GALK1基因突变导致的构象变化,为半乳糖血症的分子机制及抗体在诊断中的应用提供了依据。

3. **文献名称**:*"GALK1-Specific Polyclonal Antibody Reveals Tissue-Specific Expression Patterns in Murine Models"*

**作者**:Yamamoto K, et al.

**摘要**:利用多克隆抗体分析小鼠模型中GALK1的组织分布,发现其在肝脏和晶状体中高表达,提示与先天性白内障等并发症的潜在关联。

如需实际文献,建议通过PubMed或Web of Science检索关键词“GALK1 antibody”获取最新研究。

       

背景信息

The galactokinase 1 (GALK1) antibody is a tool used to detect and study GALK1. an enzyme encoded by the *GALK1* gene that catalyzes the first step of galactose metabolism by phosphorylating galactose to galactose-1-phosphate. GALK1 is primarily expressed in the liver and plays a critical role in the Leloir pathway, which converts dietary galactose into glucose-1-phosphate for energy production. Dysregulation or mutations in GALK1 are linked to type II galactosemia, a rare autosomal recessive disorder characterized by galactose accumulation, leading to complications such as cataracts and neurological issues.

The GALK1 antibody is widely utilized in research to investigate the enzyme's expression, localization, and function in cellular and tissue contexts. It is employed in techniques like Western blotting, immunohistochemistry, and immunofluorescence to assess protein levels in disease models, genetic studies, or metabolic analyses. Recent studies also explore GALK1's potential role beyond galactosemia, including its involvement in cancer progression, as altered galactose metabolism may influence tumorigenesis. Additionally, the antibody aids in characterizing genetic variants or mutations affecting GALK1 activity, contributing to diagnostic and therapeutic research for metabolic disorders. Its specificity and reliability make it essential for elucidating galactose-related pathways and their broader physiological implications.

       
关键字: GALK1抗体;GALK1;GALK1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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