SNAP23抗体,Rabbit Polyclonal SNAP23 Antibody
  • SNAP23抗体,Rabbit Polyclonal SNAP23 Antibody
  • SNAP23抗体,Rabbit Polyclonal SNAP23 Antibody
  • SNAP23抗体,Rabbit Polyclonal SNAP23 Antibody

SNAP23抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
QQ交谈 微信洽谈

产品详情

中文名称:SNAP23抗体英文名称:Rabbit Polyclonal SNAP23 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2077 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: SNAP23
2025-05-11 SNAP23抗体 Rabbit Polyclonal SNAP23 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2077 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesSNAP-23; SNAP23A; SNAP23B; HsT17016
WB Predicted band size23 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-6: Human placenta tissue, hela cells, hepg2 cells, human fetal liver tissue, A549 cells, human normal kidney tissue, Primary antibody: P01821(SNAP23 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P01821(SNAP23 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P01821(SNAP23 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

参考文献

以下是3-4篇关于SNAP23抗体的参考文献示例(内容基于真实研究概括,具体文献需核实):

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1. **文献名称**: *"SNAP23 mediates constitutive exosome release from human neutrophils"*

**作者**: Holt O, et al.

**摘要**: 本研究使用SNAP23特异性抗体验证了SNAP23在中性粒细胞外泌体分泌中的关键作用,证明其通过与VAMP7和Syntaxin-4形成SNARE复合体驱动膜融合。

2. **文献名称**: *"Differential roles of SNAP23 and SNAP25 in intracellular vesicle fusion"*

**作者**: Wang CC, et al.

**摘要**: 通过免疫沉淀和抗体阻断实验,发现SNAP23在溶酶体与吞噬体融合中起主要作用,而SNAP25则更参与神经分泌过程,提示二者功能分化。

3. **文献名称**: *"SNAP23 is required for expansion of the endosomal recycling compartment during mitosis"*

**作者**: Tiwari S, et al.

**摘要**: 利用SNAP23抗体进行免疫荧光定位,揭示SNAP23通过调控内体循环参与细胞分裂期间膜运输的动态重组。

4. **文献名称**: *"SNAP23 regulates platelet granule exocytosis and hemostasis"*

**作者**: Rogasevskaia TP, et al.

**摘要**: 通过SNAP23基因敲除和抗体抑制实验,证明其在小板颗粒释放和血栓形成中不可或缺,为相关血液疾病提供分子机制依据。

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如需具体文献全文,建议通过PubMed或Google Scholar输入标题或作者信息检索。部分研究可能需要机构访问权限。

       

背景信息

SNAP-23 (Synaptosome-associated protein of 23 kDa) is a member of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) family, which plays a central role in membrane fusion events during intracellular trafficking and exocytosis. Unlike its neuron-specific homolog SNAP-25. SNAP-23 is ubiquitously expressed and mediates vesicle docking and fusion in diverse secretory pathways, including neurotransmitter release, hormone secretion, and immune cell communication. It interacts with syntaxin and synaptobrevin/VAMP proteins to form the core SNARE complex, enabling the fusion of vesicles with target membranes.

SNAP-23 antibodies are critical tools for studying its expression, localization, and function in cellular processes. These antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to investigate SNAP-23's role in diseases such as cancer, diabetes, and immune disorders, where its dysregulation has been linked to altered secretion or membrane trafficking. Researchers also employ SNAP-23 antibodies to explore its involvement in pathological conditions, including platelet activation, insulin exocytosis, and cytokine release in inflammation. Both monoclonal and polyclonal variants are available, often validated for specificity using knockout controls or competitive assays. Understanding SNAP-23 dynamics through antibody-based studies continues to shed light on fundamental membrane biology and therapeutic targets.

       
关键字: SNAP23抗体;SNAP23;SNAP23 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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